Test |
Tumora |
Comentariu |
Tisut |
| EGFR
(EPIDERMAL GROWTH FACTOR RECEPTOR) |
NON
SMALL CELL LUNG CANCER (NSCLC) |
EXON
18-21 MUTATIONS (IRESSA/GEFITINIB) RESPONSIVENESS |
FRESH
TISSUE (ETHANOL-FIXED TISSUE) |
HER2
/ NEU |
BREAST
CANCER |
OVEREXPRESSION
(HERCEPTIN RESPONSIVENESS) |
PARAFFINISED
TUMOUR TISSUE |
KIT
|
GASTROINTESTINAL
STROMAL TUMOR, GIST |
MUTATIONS
IN EXONS 9, 11, 13 AND 17 (GLEEVEC/IMATINIB RESPONSIVENESS) |
PARAFFINISED
TUMOUR TISSUE |
| ACUTE
MYELOID LEUKEMIA |
MUTATIONS
IN EXONS 8, 11 AND 17 (GLEEVEC/IMATINIB RESPONSIVENESS) |
WHOLE
BLOOD, BONE MARROW ASPIRATE OR PARAFFIN-EMBEDDED BIOPSY |
| MASTOCYTOSIS |
MUTATIONS
IN EXON 17 (GLEEVEC/IMATINIB RESPONSIVENESS) |
PARAFFINISED
TUMOUR TISSUE |
| MAST
CELL LEUKEMIA |
MUTATIONS
IN EXON 17 (GLEEVEC/IMATINIB RESPONSIVENESS) |
WHOLE
BLOOD, BONE MARROW ASPIRATE OR PARAFFIN-EMBEDDED BIOPSY |
PDGFRA
(PLATELET-DERIVED GROWTH FACTOR RECEPTOR, ALPHA, PDGFR2) |
GASTROINTESTINAL
STROMAL TUMOR, GIST |
MUTATIONS
IN EXONS 12 AND 18 (GLEEVEC/IMATINIB RESPONSIVENESS) |
PARAFFINISED
TUMOUR TISSUE |
| FIP1L1
/ PDGFRA |
IDIOPATHIC
HYPEREOSINOPHILIC SYNDROME |
FUSION
OF FIP1L1 WITH PDGFRA
(GLEEVEC / IMATINIB RESPONSIVENESS)
|
WHOLE
BLOOD, BONE MARROW ASPIRATE OR PARAFFIN-EMBEDDED BIOPSY |
| FIP1L1
/ PDGFRA |
CHRONIC
EOSINOPHILIC LEUKEMIA |
FUSION
OF FIP1L1 WITH PDGFRA
(GLEEVEC / IMATINIB RESPONSIVENESS)
|
WHOLE
BLOOD, BONE MARROW ASPIRATE OR PARAFFIN-EMBEDDED BIOPSY |
MSI
- MICROSATELLITE
INSTABILITY
|
HEREDITARY
NON-POLYPOSIS COLORECTAL CANCER, HNPCC |
5
MARKERS: BAT25, BAT26, D2S123, D5S346 AND D17S250 |
PARAFFINISED
TUMOUR TISSUE AND BLOOD DNA |
MSI
- MICROSATELLITE
INSTABILITY
|
HEREDITARY
NON-POLYPOSIS COLORECTAL CANCER, HNPCC |
ADDITIONAL
MARKER : BAT40 |
PARAFFINISED
TUMOUR TISSUE |
IMMUNOHISTOCHEMISTRY |
HEREDITARY
NON-POLYPOSIS COLORECTAL CANCER, HNPCC |
ANTIBODIES
TO MLH1, MSH2 AND MSH6 |
PARAFFINISED
TUMOUR TISSUE |
KRAS |
VARIOUS
TUMORS |
MUTATIONS |
PARAFFINISED
TUMOUR TISSUE |
LOSS
OF HETEROZYGOSITY |
ANY
TUMOR |
DELETION |
PARAFFINISED
TUMOUR TISSUE AND BLOOD DNA |
